Mechanism of action of snake venom metalloproteinases in causing endothelial cell apoptosis and in inhibiting ristocetin-induced platelet aggregation

博士 === 國立臺灣大學 === 藥理學研究所 === 90 === Snake venom metalloproteinse (SVMP), which is structurally similar to ADAM (a disintegrin and a metalloproteinase domain), is a Zn2+-dependent proteinase and possesses a conserved catalytic sequence, which reads HEXXHXXGXXH. Based on their domain structures, SVMPs...

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Bibliographic Details
Main Authors: Wen-Bin Wu, 吳文彬
Other Authors: Tur-Fu Huang
Format: Others
Language:zh-TW
Published: 2002
Online Access:http://ndltd.ncl.edu.tw/handle/81944928596936574423