Design and Synthesis of Anticancer Alkylating Agents of Pyrrolo[2,1-c][1,4]benzodiazepine Containing Oxygen Group in C-ring
碩士 === 高雄醫學大學 === 天然藥物研究所 === 91 === DC-81 , an antitumor antibiotic produced by streptomyces species, belogs to the pyrrolo[2,1-c][1,4]benzodiazepines (PBDs) which are potent inhibitors of nucleic acid synthesis and block DNA transcription. They bind selectively in the minor groove of DN...
| Main Authors: | , |
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| Other Authors: | |
| Format: | Others |
| Language: | zh-TW |
| Published: |
2003
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| Online Access: | http://ndltd.ncl.edu.tw/handle/4a6nuu |