Design and Synthesis of Tail-to-tail Linked Pyrrolo[2,1-c][1,4]benzodiazepine Dimers as Antitumor Agents
碩士 === 高雄醫學大學 === 醫藥暨應用化學系碩士班 === 92 === The pyrrolo[2,1-c][1,4]benzodiazepines (PBDs)(in Figure 1) is a affiliate of potent DNA-binding antitumor antibiotics which are produced by streptomyces species. These biosynthetically derived compounds are inhibiting DNA replication on account of DNA-antibi...
| Main Authors: | , |
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| Other Authors: | |
| Format: | Others |
| Language: | zh-TW |
| Published: |
2004
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| Online Access: | http://ndltd.ncl.edu.tw/handle/02693262669485789457 |