Design and Synthesis of Indole LinkedPyrrolo[2,1-c][1,4]benzodiazepineHybrides Anticancer Alkylating Agents
碩士 === 高雄醫學大學 === 醫藥暨應用化學系碩士班 === 92 === The pyrrolo[2,1-c][1,4]benzodiazepines (PBDs) is a family of Anti-cancer agents derived form Streptomyces species. The PBDs can interact with DNA in a sequence－selective fashion，and form a covalent bond with a guanine base in the minor groove of DNA.We have s...
| Main Authors: | , |
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| Format: | Others |
| Language: | zh-TW |
| Published: |
2004
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| Online Access: | http://ndltd.ncl.edu.tw/handle/02485640249573530724 |