Study on Generation of Chemical Function Based Pharmacophore Models for Hepatitis C virus NS3 Protease Inhibitors

碩士 === 國立清華大學 === 分子醫學研究所 === 92 === Chmical function based pharmacophore models were developed for a series of pyrimidinone- and pyrazinone-based HCV NS3 protease inhibitors. The pharmacophore models were generated using a training set consisting of 20 inhibitors. The activity spread, expressed in...

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Bibliographic Details
Main Authors: Chien-Sheng Lu, 盧建勝
Other Authors: 林志侯
Format: Others
Language:zh-TW
Published: 2004
Online Access:http://ndltd.ncl.edu.tw/handle/7kx8mz