Pharmacophoric Pattern Analysis for β-Carboline-Based Inhibitors of Phosphodieasterase type 5 using 3D-QSAR approach
碩士 === 國立清華大學 === 生物資訊與結構生物研究所 === 93 === Phosphodiesterase type 5 (PDE5) is an important enzyme for controlling the levels of the intracellular cGMP which significantly corresponds to male erection dysfunction. Tadalafil, also known as Cialis, is a β-carboline derivative which inhibits PDE5 specif...
| Main Authors: | , |
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| Other Authors: | |
| Format: | Others |
| Language: | en_US |
| Published: |
2005
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| Online Access: | http://ndltd.ncl.edu.tw/handle/20024345961045694358 |