Dynamics, Conformational Transition and Drug Interactions of P-glycoprotein upon ATP Binding

碩士 === 國立臺灣大學 === 藥學研究所 === 93 === The overexpression of P-glycoprotein (Pgp) is one of the major causes of multidrug resistance (MDR) in cancer chemotherapies. Until now, it remains very challenging to obtain the high resolution Pgp structure and currently only low resolution electron microscopy st...

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Bibliographic Details
Main Authors: Hui-Hsuan Tu, 杜惠瑄
Other Authors: Jung-Hsin Lin
Format: Others
Language:zh-TW
Published: 2005
Online Access:http://ndltd.ncl.edu.tw/handle/54017745421265291780