Purification of Human APP695 and BACE1-454 and Activity Evaluation of BACE inhibitors

碩士 === 國立臺灣大學 === 藥學研究所 === 93 === β-site APP cleaving enzyme (BACE) participates in the rate-limiting step about Aβ production. It is an important target for BACE to treat AD. In order to characterize BACE catalyzed reaction by in vitro enzyme kinetic studies, establish a screening system to identi...

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Bibliographic Details
Main Authors: Kai-Wei Lin, 林愷薇
Other Authors: 孔繁璐
Format: Others
Language:zh-TW
Published: 2005
Online Access:http://ndltd.ncl.edu.tw/handle/58304120481924396834