Design and Synthesis of Tail-to-tail Linked Pyrrolo[2,1-c][1,4]benzodiazepine Dimers and Hybride as Antitumor Agents

碩士 === 高雄醫學大學 === 醫藥暨應用化學研究所碩士班 === 94 === Pyrrolo[2,1-c][1,4]benzodiazepines (PBDs) are a group of potent, naturally occurring antitumor antibiotics produced by Streptomyces species. Recently, we reported a series of novel PBD linked with indole carboxylates. Preliminary in vivo tests show that...

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Bibliographic Details
Main Authors: Wen-Yu Chung, 鐘雯郁
Other Authors: 王志鉦
Format: Others
Language:zh-TW
Published: 2006
Online Access:http://ndltd.ncl.edu.tw/handle/77337731193785794704