The antioxidant role of PGI2 on HIF-1a stabilization and therapy of pulmonary hypertension
博士 === 國防醫學院 === 生命科學研究所 === 94 === Abstract We investigated the antioxidant effect of PGI2 on HIF-1 regulation in human umbilical vein endothelial cells (HUVECs) and the therapy of MCT-caused pulmonary hypertension. HIF-1α, a subunit of HIF-1, is rapidly degraded under normoxic conditions. Hypoxia...
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| Format: | Others |
| Language: | zh-TW |
| Published: |
2005
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| Online Access: | http://ndltd.ncl.edu.tw/handle/45111799521972926309 |