Investigation of the neurodegenerative impact of CAG expansion in TBP gene through Taiwan neurodegenerative patients and transgenic mouse model

碩士 === 國立臺灣師範大學 === 生命科學研究所 === 94 === TATA binding protein (TBP) is a general transcription factor that plays an important role in initiation of transcription. TBP gene is located in chromosome 6q27 and contains a CAG/CAA trinucleotide repeats region in 5’ end which encodes a polyglutamine tract. I...

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Bibliographic Details
Main Author: 林承岳
Other Authors: Hsiu-Mei Hsieh-Li
Format: Others
Language:zh-TW
Published: 2006
Online Access:http://ndltd.ncl.edu.tw/handle/88055471199656175138