TNF-α enhances serine/threonine phosphorylation of γ-secretase via a JNK-dependent MAPK pathway
碩士 === 國立臺灣大學 === 動物學研究研究所 === 94 === Amyloid-β (Aβ), which is generated through β- and γ-secretase-mediated proteolysis of amyloid precursor protein (APP), plays a critical role in the pathogenesis of Alzheimer’s disease (AD). γ-Secretase which cleaves Amyloid-β precursor protein (APP) in its trans...
| Main Authors: | , |
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| Other Authors: | |
| Format: | Others |
| Language: | en_US |
| Published: |
2006
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| Online Access: | http://ndltd.ncl.edu.tw/handle/23089240532836296485 |