Functional study of Cx26 and Cx30 mutants in nonsyndromic deafness by using Tet-on system

碩士 === 中山醫學大學 === 生物醫學科學學系碩士班 === 95 === Gap junction is formed by end-to-end docking of two connexons, hexamers of connexin (Cx) protein, expressed on neighboring cells. It is associated with potassium cycle in cochlear. Mutations in Cx often lead to hearing loss. Three heterozygous mutations, Cx26...

Full description

Bibliographic Details
Main Authors: Chia-Chen, 張嘉真
Other Authors: 李宣佑
Format: Others
Language:zh-TW
Published: 2007
Online Access:http://ndltd.ncl.edu.tw/handle/81714637087270462538