Improving Signal Intensity in the Analysis of Peptides with Trifluoroacetic Acid-containing Mobile Phase by Reversed-Phase Capillary Liquid Chromatography-electrospray Mass Spectrometry

碩士 === 國立臺灣大學 === 化學研究所 === 95 === Trifluoroacetic acid (TFA) is a commonly used ion-pair reagent in RP-HPLC to improve peak shape and enhance separation efficiency of peptides. However, TFA forms very strong ion pairs with peptides that are not broken apart in the process of electrospray ionization...

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Bibliographic Details
Main Authors: Wan-Li Lee, 李宛俐
Other Authors: 何國榮
Format: Others
Language:zh-TW
Published: 2007
Online Access:http://ndltd.ncl.edu.tw/handle/79820228600975631148