The role of lipid rafts in the spatial and functional correlations between γ-secretase and the proteolysis of amyloid precursor protein C-terminal fragments
碩士 === 臺灣大學 === 動物學研究研究所 === 95 === Amyloid plaque is the hallmark in Alzheimer’s disease (AD) brains. It is composed of amyloid β-peptide (Aβ) deposits. Aβ is produced through a series of cleavages of amyloid precursor protein (APP) by β- and γ-secretases. The γ-cleavage of the 99-amino acid carbox...
| Main Authors: | , |
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| Other Authors: | |
| Format: | Others |
| Language: | en_US |
| Published: |
2007
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| Online Access: | http://ndltd.ncl.edu.tw/handle/35004776584340150368 |