Effects of ultrasound-degraded konjac flour with varying molecular weights on the intestinal physiology and serum lipids in rats

• Main Authors: Liang-Yi Cheng, 鄭良益
• Other Authors: Kuo-Wei Lin
• Format: Others
• Language: zh-TW
• Published: 2006
• Online Access: http://ndltd.ncl.edu.tw/handle/66180793678865292911

碩士 === 靜宜大學 === 食品營養研究所 === 95 === Konjac glucomannan (KGM) is not hydrolyzed by digestive enzymes in human intestine and is considered as an indigestible dietary fiber. The main component of konjac consists on β-(1→4) linked D-glucose and D-mannose units. Researches indicate that KGM belongs to water-soluble dietary fiber regulating the serum triacylglycerol and cholesterol. Because cholesterol-lowering mechanism of konjac is associated with its viscosity in intestine, this study was initiated to investigate the influences of ultrasound-degraded konjac flour for 0 min (1017 kDa), 8 min (699 kDa) and 15 min (576 kDa) on the physiology of male Sprague-Dawley rats fed for 6 weeks. Analyses included food intake, average daily gain (ADG), feed efficiency ratio (FER), epididymal fat pad, serum triacylglycerol, total cholesterol, high and low-density lipoprotein cholesterol, fecal moisture content, and digestibility. Results indicated that high molecular weight konjac diet had lower food intake, ADG and FER than other treatments. Comparing to cellulose control (CEL), rats fed with konjac diets showed increased fecal and cecum weight but decreased fat and protein crude digestibility and low density lipoprotein by 4.6-7.9%, 2.9-3.8%, and 24.3-30.3%, respectively. Significantly lower liver triacylglycerol was found to rats fed with high molecular weight konjac. Results also showed that konjac molecular weight ranged 570 to 700 kDa could increase fecal weight and reduce fat accumulation in liver.