Establishment of a BACE Inhibitor Screening Model Based on Human Platelet Protein and Its Application on Development of Natural Compounds

碩士 === 國立陽明大學 === 藥理學研究所 === 96 === The processing of amyloid precursor protein is initiated by beta-site APP cleaving enzyme (BACE) cleavage, which �nproduce beta-cleaved C-terminal fragment (C99), and then further cleaved by ��-secretase leads to ��-amyloid (A���w formation. Deposition of A�� is i...

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Bibliographic Details
Main Authors: Ya-Wen Yang, 楊雅雯
Other Authors: Wei-Jern Tsai
Format: Others
Language:zh-TW
Published: 2008
Online Access:http://ndltd.ncl.edu.tw/handle/06042323253580995573