Molecular mechanism underlying mutant PINK1-induced degeneration of substantia nigra dopaminergic neurons

碩士 === 長庚大學 === 生物醫學研究所 === 97 === Parkinson’s disease (PD) is the most common neurodegenerative motor disorder. Missense or truncating mutations of phosphatase and tesin homologue (PTEN)-induced kinase 1 (PINK1) gene are implicated in the pathogenesis of familial type 6 of Parkinson’s disease (PARK...

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Bibliographic Details
Main Authors: Ai Shun Wu, 吳艾瑄
Other Authors: H. L. Wang
Format: Others
Published: 2009
Online Access:http://ndltd.ncl.edu.tw/handle/10982021337048845171