Synthesis of 3-(5-Methyl-2-furyl)-1,5-diphenylpyrazole Derivatives as Antiplatelet Agents
碩士 === 中國醫藥大學 === 藥物化學研究所碩士班 === 97 === In continuing development of novel aniplatelet agents, we had found that 3-(5-methyl-2-furyl)-1,5-diphenylpyrazole ( I) showed good platelet inhibitory activity. The mechanism is inhibition of cyclic nucleotide phosphodiesterase 5 (IC50 = 4.21 μM). Encouraged...
| Main Authors: | , |
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| Other Authors: | |
| Format: | Others |
| Language: | zh-TW |
| Published: |
2009
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| Online Access: | http://ndltd.ncl.edu.tw/handle/66580816427067903733 |