Design and Synthesis of Pyrrolo[2,1-c][1,4]benzodiazepine Hybrids agent and Dimers as Antitumor Alkylation Agents

碩士 === 高雄醫學大學 === 醫藥暨應用化學研究所 === 97 === Pyrrolo[2,1-c][1,4]benzodiazepines (PBDs) are natural products extracted from many kinds of Streptomyces, and exhibited high bioactivities of anti-biotics and anti-tumors in past reports.The PBDs can be interact with DNA in high sequence – selective active, be...

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Bibliographic Details
Main Authors: Chung-Yu Chen, 陳建宇
Other Authors: Jeh-Jeng Wang
Format: Others
Language:zh-TW
Published: 2009
Online Access:http://ndltd.ncl.edu.tw/handle/cgavpj