The Signaling Pathways of DNA Damager MNNG- Induced Necrotic Cell Death
碩士 === 國立臺灣大學 === 藥理學研究所 === 97 === Alkylating agent N-methyl-N’-nitro-N’-nitrosoguanidine (MNNG) can cause excess DNA strands break then leads to PARP-1 overactivation and necrotic cell death. However, the regulatory mechanism of PARP-1 activation in detail relating to identified necrotic features,...
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| Format: | Others |
| Language: | en_US |
| Published: |
2009
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| Online Access: | http://ndltd.ncl.edu.tw/handle/64877128791196498101 |