Functional studies of the α- and β-human 8-oxoguanine DNA glycosylase 1 in mitochondrial DNA repair
碩士 === 國立成功大學 === 醫學檢驗生物技術學系碩博士班 === 98 === 8-oxo-7,8-dihydroguanine (8-oxoG) is the major mutagenic base lesion in DNA caused by reactive oxygen species (ROS) and accumulates in both nuclear and mitochondrial DNA. It is associated with tumorigenesis because its miscoding nature to adenine and it ca...
| Main Authors: | , |
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| Other Authors: | |
| Format: | Others |
| Language: | en_US |
| Published: |
2010
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| Online Access: | http://ndltd.ncl.edu.tw/handle/25630979816517562872 |