Chemical Probe-Based Approach to Delineate the Underlying Mechanism for Nitric Oxide-Mediated Inactivation of Protein Tyrosine Phosphatases in Regulation of Insulin Signaling
博士 === 臺灣大學 === 生化科學研究所 === 98 === Enzymes in the protein tyrosine phosphatase (PTP) superfamily are involved in the regulation of many aspects of biological processes. The catalytic activity of PTPs is mediated by an invariant Cys residue, which has a remarkably low pKa, therefore being able to car...
Main Authors: | , |
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Other Authors: | |
Format: | Others |
Language: | en_US |
Published: |
2010
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Online Access: | http://ndltd.ncl.edu.tw/handle/28894300698434482551 |