Design, synthesis and bioassays of peptidic antagonists of Grb2 SH2 domain and Id1 for development of anticancer agents

博士 === 東海大學 === 化學系 === 98 === The growth factor receptor-bound protein-Src homology 2 (Grb2 SH2) plays an important role in the oncogenic Ras signaling pathway, which involves in cell proliferation and differentiation. Therefore, we focus on developing peptidic inhibitors of the Grb2 SH2 domain as...

Full description

Bibliographic Details
Main Authors: Chiu-Heng, Chen, 陳丘泓
Other Authors: Feng-Di Tiffany, Lung
Format: Others
Language:en_US
Online Access:http://ndltd.ncl.edu.tw/handle/20230595933355358657