Synthesis of IMD-0354 analogs and their inhibition on TNF-α induced NF-κB activation
碩士 === 東海大學 === 化學系 === 98 === Nuclear factor (NF)-κB is an important transcription factor. When a cell is stimulated by stress, over activated NF-κB would result in unexpected proliferation or death of the cell. Several studies demonstrated that IMD-0354 was a good inhibitor for NF-κB, we therefore...
| Main Authors: | , |
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| Other Authors: | |
| Format: | Others |
| Language: | zh-TW |
| Published: |
2010
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| Online Access: | http://ndltd.ncl.edu.tw/handle/45682962830956367401 |