The Correlation between the Polymorphism of Glutathione S-transferases Pi 1(GSTP1) and Cisplatin- or Carboplatin-induced Nephrotoxicity

碩士 === 臺北醫學大學 === 藥學研究所 === 98 === Background and aims: Cisplatin and carboplatin induced nephrotoxicity is a major dose-limiting factor for platinum-based treatments. Glutathione S-transferase Pi (GSTP) catalyzes the glutathione-conjugation as the first and the key step of nephrotoxin formation fr...

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Bibliographic Details
Main Authors: Kai-Wen Shih, 石凱文
Other Authors: 陳香吟
Format: Others
Language:zh-TW
Published: 2010
Online Access:http://ndltd.ncl.edu.tw/handle/33559762868147472940