Construction of an oncolytic adenovirus for KRAS activating mutant colorectal cancer cells

博士 === 國立陽明大學 === 生化暨分子生物研究所 === 98 === Abstract E1B-55kD-deleted adenoviruses (ΔE1B-55kD Ads) have been used as conditionally replicative adenoviruses (CRAds) for therapeutic purpose in tumors with loss-of-function p53 mutation. To target cancer cells harboring activating mutant KRAS (KRASaMut) b...

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Bibliographic Details
Main Authors: Chin-Cheng Liu, 劉錦誠
Other Authors: Ying-Chieh Tsai
Format: Others
Language:zh-TW
Published: 2010
Online Access:http://ndltd.ncl.edu.tw/handle/75160038999894140520