Studies of Trans-Acting TW17 ribozyme Catalysis Systems to Decipher Its Phosphorothiolate Thiolester Hydrolysis Mechanism

碩士 === 高雄醫學大學 === 醫藥暨應用化學研究所 === 99 === 英文摘要 The TW17 RNA is a unique Zn2+-dependent ribozyme capable of performing cis-acting catalysis to hydrolyze a phosphorothiolate thiolester bond between the RNA molecule and its substrate. The objectives of the study are to further decipher the reaction mecha...

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Bibliographic Details
Main Authors: Yi-Ming Liou, 劉宜明
Other Authors: Tzu-Pin Wang
Format: Others
Language:zh-TW
Published: 2011
Online Access:http://ndltd.ncl.edu.tw/handle/54991295890093656380