Apoptosis-inducing, Anti-migratory, and Anti-angiogenic Effects of a Novel DC-81-indole Conjugate Agent on Cultured Human Melanoma A375 Cells

博士 === 高雄醫學大學 === 藥學研究所 === 99 === Pyrrolo[2,1-c][1,4]benzodiazepine (PBD) chemicals are antitumor antibiotics inhibiting nucleic acid synthesis. An indole carboxylate-PBD hybrid with six-carbon spacer structure (IN6CPBD) has been previously demonstrated to induce melanoma cell apoptosis and reduce...

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Bibliographic Details
Main Authors: Ming-Chu Hsieh, 謝銘珠
Other Authors: Jeh -Jeng Wang
Format: Others
Language:zh-TW
Published: 2011
Online Access:http://ndltd.ncl.edu.tw/handle/04647523613704794683