A web server for lead optimization using site‐moiety map:A case study on neuraminidase

碩士 === 國立交通大學 === 生物資訊及系統生物研究所 === 99 === The optimization process of initial hits is one of the major challenges in drug development because the initial hits found by high-throughput screening or virtual screening are usually at the micromolar level, Computer-aided lead optimization method can be r...

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Bibliographic Details
Main Authors: Huang,Yu-Che, 黃御哲
Other Authors: Yang,Jinn-Moon
Format: Others
Language:zh-TW
Published: 2011
Online Access:http://ndltd.ncl.edu.tw/handle/78657018670928489075