Synthesis and Pharmacological Evaluation of N-Substituted Arylsulfonamide Derivatives asNew γ-Secretase Inhibitors
碩士 === 國防醫學院 === 藥學研究所 === 99 === Alzheimer’s disease (AD) is an irreversible, progressive neurodegenerative disease characterized by beta-amyloid (Aβ) deposition and neurofibrillary tangles (NFTs) formation. The overproduction and accumulation of Aβ are key pathogenic events in AD progression. Aβ i...
| Main Authors: | , |
|---|---|
| Other Authors: | |
| Format: | Others |
| Language: | zh-TW |
| Published: |
2011
|
| Online Access: | http://ndltd.ncl.edu.tw/handle/00797993498231743572 |