Synthesis and biological activity of naphthyridine derivatives as potential Akt inhibitors
碩士 === 東海大學 === 化學系 === 99 === PI3K/Akt signaling pathway plays a key role in human cancers. Overexpression of Akt causes abnormal cell proliferation and result in cancer. Therefore, Akt is an attractive therapeutic target for cancer treatment. We have designed series of aminoindole and naphthyridin...
| Main Authors: | , |
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| Format: | Others |
| Language: | zh-TW |
| Published: |
2011
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| Online Access: | http://ndltd.ncl.edu.tw/handle/52256652298518462423 |