Analyzing C-terminal alternative splicing of Cav2.1and developing the Splice-Isoform-Specific RNAi as apotential therapeutic strategy for SCA6
博士 === 國立陽明大學 === 神經科學研究所 === 99 === Spinocerebellar ataxia type 6 (SCA6) is an inherited neurodegenerative disorder characterized by the preferential degeneration of cerebellar Purkinje cells. SCA6 is caused by a polyglutamine (polyQ)-coding CAG repeat expansion in the 3’ end of the CACNA1A gene, w...
| Main Authors: | , |
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| Other Authors: | |
| Format: | Others |
| Language: | zh-TW |
| Published: |
2011
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| Online Access: | http://ndltd.ncl.edu.tw/handle/67428207508990682896 |