Analyzing the anti-cancer potential of G-quadruplex stabilizing- carbazole derivatives

博士 === 國立陽明大學 === 生物藥學研究所 === 99 === Telomerase is the enzyme responsible for extending G-strand telomeric DNA and represents a promising target for neoplasia therapeutic treatments. Inhibition of telomerase can be achieved by stabilization of G-quadruplex DNA structures. Here we characterized the c...

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Bibliographic Details
Main Authors: Fong-Chun Huang, 黃豐淳
Other Authors: Jing-Jer Lin
Format: Others
Language:zh-TW
Published: 2011
Online Access:http://ndltd.ncl.edu.tw/handle/44465977333831502583