Modulatory Effects of Transcriptional Repressor B Lymphocyte-induced Maturation Protein-1 (Blimp-1) on the Development and Function of T Cells in Non-obese Diabetic (NOD) Mice: Using Tissue-specific Transgenic and/or Knockout Approaches

博士 === 國防醫學院 === 醫學科學研究所 === 100 === Recently, Blimp-1 expands its control over T cells and is associated with susceptibility to colitis in mice with T cell-specific Blimp-1 deficiency. We demonstrate that transgenic expression of Blimp-1 in T cells significantly decreases the incidence of diabetes...

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Bibliographic Details
Main Authors: Lin, Ming-Hong, 林明宏
Other Authors: Sytwu, Huey-Kang
Format: Others
Language:en_US
Published: 2012
Online Access:http://ndltd.ncl.edu.tw/handle/56208573516838959982