Virtual Screening ofEnzyme Inhibitors for Two KinasesUsing Docking Computation：Effects of Flexible Side Chains and Hinge Hydrogen BondConstraints
碩士 === 國立臺灣師範大學 === 化學系 === 100 === In the present study, we carried out docking computation of compounds against two kinases, CDK2 and c-MET, using GOLD program. Both are of pharmaceutical interest. In the part of CDK2 kinase, we investigated if allowing side chains to move and applying hydrog...
| Main Authors: | , |
|---|---|
| Other Authors: | |
| Format: | Others |
| Language: | zh-TW |
| Published: |
2012
|
| Online Access: | http://ndltd.ncl.edu.tw/handle/08334843882354432552 |