The C-terminus of PARK2 is required for its self-interaction, solubility and role in the spindle assembly checkpoint
博士 === 慈濟大學 === 醫學科學研究所 === 100 === Abstract PARK2, an ubiquitin ligase closely correlated with Parkison’s disease and cancer, has been shown to accumulate at centrosomes to ubiquitinate misfolded proteins accumulated during interphase. In the present study, we demonstrated that PARK2 can also local...
Main Authors: | , |
---|---|
Other Authors: | |
Format: | Others |
Language: | en_US |
Published: |
2012
|
Online Access: | http://ndltd.ncl.edu.tw/handle/26228367715558972717 |