Virtual screening and synthesis of potential Akt inhibitors
碩士 === 東海大學 === 化學系 === 100 === Protein kinase B/Akt is a central node of the PI3K/Akt signaling pathway that is believed to be the most frequently mutated or overexpressed signaling abnormality in human cancers. In this study, we have taken SS3, an Akt inhibitor developed by Abbott Laboratory, as a...
| Main Authors: | , |
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| Format: | Others |
| Language: | zh-TW |
| Published: |
2012
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| Online Access: | http://ndltd.ncl.edu.tw/handle/68301634573952420998 |