Effect of down-regulation of hMMS21 on the growth of HCT116 colorectal cancer cells
碩士 === 國立陽明大學 === 生化暨分子生物研究所 === 100 === MMS21 is a SUMO E3 ligase required for DNA damage repair. Previous study in our laboratory demonstrated that MMS21 depletion in MCF7 breast cancer cells will impairs G1-S phase transition due to lowered E2F1 protein levels and cyclin E-CDK2 activity. The decr...
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| Other Authors: | |
| Format: | Others |
| Language: | en_US |
| Published: |
2012
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| Online Access: | http://ndltd.ncl.edu.tw/handle/63485631155312964729 |