Determination of Tissue Distribution of Potent Antitumor Agent Ureidomustin (BO-1055) by HPLC and Its Pharmacokinetic Application in Rats

碩士 === 國立陽明大學 === 藥理學研究所 === 100 === Ureidomustin hydrochloride (BO-1055) is a chemically stable and water-soluble phenyl N-mustard pharmacophore, which exhibits a broad spectrum of antitumor activity in vitro and in vivo and has no cross-resistance to taxol or vinblastine. However, the pre-clinical...

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Bibliographic Details
Main Authors: Shin-I Chien, 簡欣怡
Other Authors: Jiin-Cherng Yen
Format: Others
Language:zh-TW
Published: 2012
Online Access:http://ndltd.ncl.edu.tw/handle/25365050673952057686