The Effects of Sulfasalazine and Endoplasmic Reticulum-Targeted Antigenic Peptides on The Formation of HLA-B27 Heavy ChainDimer, A Key Molecule in The Pathogenesis ofAnkylosing Spondylitis.
博士 === 國立中正大學 === 分子生物研究所 === 102 === Ankylosing spondylitis (AS) is strongly associated with the expression of human leukocyte antigen-B27 (HLA-B27). HLA-B27 heavy chain (HC) has a propensity to fold slowly resulting in the accumulation of misfolded HLA-B27 HC in the ER, triggering the unfolded pro...
| Main Authors: | , |
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| Format: | Others |
| Language: | zh-TW |
| Published: |
2012
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| Online Access: | http://ndltd.ncl.edu.tw/handle/93194365877312055207 |