GSKIP is required for mitochondrial fission protein Drp1 phosphorylation via distinct GSK3 and PKA binding domains, conferring neuroprotection under H2O2 induced-oxidative stress.
碩士 === 高雄醫學大學 === 生物化學研究所 === 101 === GSKIP has been identified as smallest A-kinase anchor proteins (AKAP), and retains both PKA and GSK3beta binding domains. The GSK3β binding of GSKIP is linked to neurite outgrowth, but no physiological significance was found for its PKA binding. In this study, w...
| Main Authors: | , |
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| Other Authors: | |
| Format: | Others |
| Language: | zh-TW |
| Published: |
2013
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| Online Access: | http://ndltd.ncl.edu.tw/handle/60941515736217594911 |