Role of the Candidate Tumor Suppressor BTG3 in Maintenance of Genomic Stability and Tumorigenesis
博士 === 國防醫學院 === 生命科學研究所 === 101 === BTG3 is a member of the antiproliferative BTG/Tob gene family and its expression is induced by genotoxic stress in a p53 and CHK1-dependent manner. BTG3 interacts with and inhibits E2F1 to regulate cell proliferation. BTG3 depletion promotes cancer cell proli...
Main Authors: | , |
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Other Authors: | |
Format: | Others |
Language: | en_US |
Published: |
2013
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Online Access: | http://ndltd.ncl.edu.tw/handle/10508367785194097895 |