Therapeutic Strategies Targeting Chaperone and Proteasome for PolyQ-mediated SCA
碩士 === 國立臺灣師範大學 === 生命科學研究所 === 101 === In polyQ-mediated disorders, the expansions of translated CAG repeats in the disease genes result in long polyQ tracts in the respective proteins, leading to intranuclear and cytoplasmic accumulation of aggregated polyQ proteins inside neurons. The molecular c...
| Main Authors: | , |
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| Other Authors: | |
| Format: | Others |
| Language: | en_US |
| Published: |
2013
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| Online Access: | http://ndltd.ncl.edu.tw/handle/78487253229526434106 |