Structural Studies of Human Topoisomerase IIβ and its Interactions with Anticancer Drugs

博士 === 國立臺灣大學 === 生物化學暨分子生物學研究所 === 101 === Type II topoisomerases (Top2s) are essential enzymes responsible for the timely resolution of DNA topological problems by temporally cleaving both strands of a DNA duplex to allow the passage of another. Agents that perturb the Top2-mediated DNA cleavage/r...

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Bibliographic Details
Main Authors: Chyuan-Chuan Wu, 吳權娟
Other Authors: 詹迺立
Format: Others
Language:en_US
Published: 2013
Online Access:http://ndltd.ncl.edu.tw/handle/14098263540552072838