Structural Studies of Human Topoisomerase IIβ and its Interactions with Anticancer Drugs
博士 === 國立臺灣大學 === 生物化學暨分子生物學研究所 === 101 === Type II topoisomerases (Top2s) are essential enzymes responsible for the timely resolution of DNA topological problems by temporally cleaving both strands of a DNA duplex to allow the passage of another. Agents that perturb the Top2-mediated DNA cleavage/r...
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| Other Authors: | |
| Format: | Others |
| Language: | en_US |
| Published: |
2013
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| Online Access: | http://ndltd.ncl.edu.tw/handle/14098263540552072838 |