Human ABCB1 (P-glycoprotein/MDR1) and ABCG2 (BCRP/MXR) Mediate Resistance to Polo-like kinase 1 inhibitors
碩士 === 長庚大學 === 生物醫學研究所 === 102 === The overexpression of the serine/threonine specific polo-like kinase 1 (Plk1) has been detected in various types of cancer, and thus has fast become an attractive therapeutic target for cancer therapy. Plk1 inhibitors BI 2536, volasertib and GSK461364, were design...
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| Format: | Others |
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2014
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| Online Access: | http://ndltd.ncl.edu.tw/handle/48402034791397339617 |