The Mechanism of Oxime-containing Naphthol Derivatives on Reduction of Intracellular Oxidative Stress Through Nrf-2 Activation
碩士 === 中國醫藥大學 === 藥物化學研究所碩士班 === 102 === Nrf-2 protein is a transcription factor that binds to Antioxidant-response element (ARE) regions and drives various detoxification and phase 2 metabolic enzymes, such as HO-1 and glutathione synthase. Activation of Nrf-2/ARE pathway is considered to protect c...
| Main Authors: | , |
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| Other Authors: | |
| Format: | Others |
| Language: | en_US |
| Published: |
2014
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| Online Access: | http://ndltd.ncl.edu.tw/handle/6uqx5a |