Antibacterial activities of fermentation broths from indogenous bacteria.

• Main Authors: Jui-Wen Lu, 呂瑞雯
• Other Authors: Chi-Chen Lin
• Format: Others
• Language: zh-TW
• Published: 2014
• Online Access: http://ndltd.ncl.edu.tw/handle/92585683221106003367

碩士 === 國立中興大學 === 生命科學院碩士在職專班 === 102 === An antibiotic is an agent that either kills or inhibits the growth of a microorganism and iscurrently used for medical treatments. However, the overuse of antibiotic results in the emerging of the multidrug-resistant bacteria. There is a need to develop new antibiotics to treat the life-threatening infections caused by the resistant strains. In this study, GRC02-4-3 and GRC86-3-4-4b were isolated from indogenous bacterial fermentations.The minimum inhibitory concentration of GRC02-4-3 was 8 μg/ml for Escherichia coli, 32 μg/ml for Staphylococcus aureus, 32 μg/ml for Methicillin-resistant Staphylococcus aureus and 8 μg/ml for Mycobacterium smegmatis. The minimum inhibitory concentration of GRC86-3-4-4b minimum inhibitory concentration was 8 μg/ml for Escherichia coli, 0.25 μg/ml for Staphylococcus aureus, 2 μg/ml for Methicillin-resistant Staphylococcus aureus and 0.5 μg/ml for Mycobacterium smegmatis.