Enhancement of p38 MAPK signal mediated MutS homologue-2 (MSH2) expression in regulating gefitinib combinaned with metformin induced cytotoxicity in human lung squamous cancer cells

碩士 === 國立嘉義大學 === 生化科技學系研究所 === 102 === Gefitinib, a selective EGFR tyrosine kinase inhibitor, has a significant activity of the antiproliferative and proapoptotic both in vitro and in vivo. Human MutS homologue-2 (MSH2) plays a central role in promoting genetic stability by correcting DNA replicatio...

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Bibliographic Details
Main Authors: Hsien-Chun Chiu, 邱憲君
Other Authors: Yun-Wei Lin
Format: Others
Language:zh-TW
Online Access:http://ndltd.ncl.edu.tw/handle/80535281304624510297